| 產品編號 | bs-4180R |
| 英文名稱 | P2Y2 Rabbit pAb |
| 中文名稱 | 嘌呤ATP受體抗體 |
| 別 名 | P2Y2R; ATP receptor; HP2U; Human P2U nucleotide receptor mRNA complete cds; P2RU1; P2RY2; P2RY2_HUMAN; P2U nucleotide receptor; P2U purinoceptor 1; P2U1; P2UR; P2Y purinoceptor 2; P2Y2; P2Y2R; Purinergic receptor; Purinergic receptor P2Y G protein coupled |
 |
Specific References (3) | bs-4180R has been referenced in 3 publications.
[IF=4.162] Zhen-Ni Liu. et al. Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway. DRUG DES DEV THER. Drug Des Dev Ther. 2022 Apr;16:1107-1120 IHC ; Mouse.
[IF=3.361] Liu ZN et al. Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation. Int Immunopharmacol. 2019 Oct 19;77:105915. WB ; Mouse.
[IF=1.42] Liu, Yuan-Mei, et al. "Expression of the P2Y2 receptor in the terminal rectum of fetal rats with anorectal malformation." International Journal of Clinical and Experimental Medicine 8.2 (2015): 1669-1676. IHC-P ; Rat.
|
| 研究領域 | 免疫學 轉錄調節(jié)因子 G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human (predicted: Mouse,Rat,Rabbit,Dog,Horse) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P2Y2R: 21-120/377 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]. Function: Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Spleen, testis, kidney, liver, lung, heart and brain. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P41231 Gene ID: 5029 Database links: Entrez Gene: 5029 Human Entrez Gene: 18442 Mouse Omim: 600041 Human SwissProt: P41231 Human SwissProt: P35383 Mouse Unigene: 339 Human Unigene: 3000 Mouse Unigene: 11102 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
