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ASAM Rabbit pAb (bs-6022R)  
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產(chǎn)品編號 bs-6022R
英文名稱 ASAM Rabbit pAb
中文名稱 脂肪細胞特異性粘附分子抗體
別    名 ACAM; Adipocyte specific adhesion molecule; CAR like membrane protein; CLMP; Coxsackie and adenovirus receptor like membrane protein; CLMP_HUMAN.  
Specific References  (1)     |     bs-6022R has been referenced in 1 publications.
[IF=6.792] Zhao D et al. PCB52 exposure alters the neurotransmission ligand-receptors in male offspring and contributes to sex-specific neurodevelopmental toxicity. Environ Pollut.2020 Sep;264:114715.  WB ;  Rat.  
研究領域 免疫學  信號轉(zhuǎn)導  細胞表面分子  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ASAM/ACAM: 15-110/373 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The CTX family of proteins, including ASAM, are type I transmembrane proteins within the Ig superfamily that localize to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion.

Function:
May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity.

Subunit:
Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein (Potential).

Subcellular Location:
Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein (Potential).

Tissue Specificity:
Predominantly expressed in epithelial cells within different tissues and in the white adipose tissue. Expressed at high levels in small intestine and placenta, at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney and lung and at low levels in the liver and peripheral blood leukocytes.

Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
Q9H6B4

Gene ID:
79827

Database links:

Entrez Gene: 79827 Human

Entrez Gene: 71566 Mouse

Entrez Gene: 286939 Rat

Omim: 611693 Human

SwissProt: Q9H6B4 Human

SwissProt: Q8R373 Mouse

SwissProt: Q8K1G0 Rat

Unigene: 591949 Human

Unigene: 280560 Mouse

Unigene: 163013 Rat



產(chǎn)品圖片
Sample: HepG2 Cell Lysate at 40 ug Primary: Anti-ASAM (bs-6022R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 39 kD Observed band size: 44 kD
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