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STARD8 Rabbit pAb (bs-6159R)  
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產(chǎn)品編號(hào) bs-6159R
英文名稱(chēng) STARD8 Rabbit pAb
中文名稱(chēng) GTP酶激活因子STARD8抗體
別    名 Deleted in liver cancer 3; DLC3; StAR related lipid transfer protein 8; START domain containing protein 8; START GAP3; STAR8_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  G蛋白偶聯(lián)受體  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 113 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human STARD8: 561-660/1023 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor.

Function:
Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1

Subunit:
Binds both the SH2 and PTB domains of TNS1.

Subcellular Location:
Binds both the SH2 and PTB domains of TNS1.

Tissue Specificity:
Widely expressed with highest levels in kidney, lung and placenta.

Similarity:
Contains 1 Rho-GAP domain.
Contains 1 START domain.

SWISS:
Q92502

Gene ID:
9754

Database links:

Entrez Gene: 9754 Human

Omim: 300689 Human

SwissProt: Q92502 Human



產(chǎn)品圖片
Sample: K562(Human) Cell Lysate at 30 ug Primary: Anti- STARD8 (bs-6159R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 113 kD Observed band size: 113 kD
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