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HMPH Rabbit pAb (bs-6600R)  
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產品編號 bs-6600R
英文名稱 HMPH Rabbit pAb
中文名稱 同源盒蛋白PRH抗體
別    名 Hematopoietically expressed homeobox; Hematopoietically-expressed homeobox protein HHEX; HEX; HHEX; HHEX_HUMAN; HMPH; Homeobox protein HEX; Homeobox protein PRH; HOX11L PEN; PRH; PRHX.  
研究領域 發(fā)育生物學  信號轉導  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 30 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HHEX/HMPH: 131-230/270 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.

Function:
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity).

Subcellular Location:
Nucleus (Probable).

Tissue Specificity:
Liver and promyelocytic leukemia cell line HL60.

Similarity:
Contains 1 homeobox DNA-binding domain.

SWISS:
Q03014

Gene ID:
3087

Database links:

Entrez Gene: 3087 Human

Entrez Gene: 15242 Mouse

Entrez Gene: 397232 Pig

Entrez Gene: 79237 Rat

Omim: 604420 Human

SwissProt: Q03014 Human

SwissProt: P43120 Mouse

Unigene: 118651 Human

Unigene: 33896 Mouse

Unigene: 12188 Rat



產品圖片
Sample: K562(Human) Cell Lysate at 30 ug Primary: Anti-HMPH? (bs-6600R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 30 kD
Sample: HL60(Human) Cell Lysate at 30 ug Primary: Anti-HMPH? (bs-6600R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 30 kD
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