| 產(chǎn)品編號(hào) | bs-11286R |
| 英文名稱(chēng) | lipocalin 1/LCN1 Rabbit pAb |
| 中文名稱(chēng) | 脂質(zhì)運(yùn)載蛋白1抗體 |
| 別 名 | LCN1; LCN1_HUMAN; Lipocalin 1(protein migrating faster than albumin, tear prealbumin); Lipocalin 1 like 2; Lipocalin-1; lipocalin 1; PMFA; Tear lipocalin; Tear prealbumin; Tlc; TP antibody VEG protein; VEGP; Von Ebner gland protein. |
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Specific References (1) | bs-11286R has been referenced in 1 publications.
[IF=5.123] Jia, W. et al. Elimination terminal fixed region screening and high-throughput kinetic determination of aptamer for lipocalin-1 by surface plasmon
resonance imaging, (2018) Analytica Chimica Acta SPRi chip ;
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| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 泛素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 17 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human lipocalin 1: 101-176/176 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Lipocalin-1 is a secretory protein that is highly expressed in fluids covering epithelial surfaces such as tears and respiratory secretions. This major lipid-binding protein in tears is also called tear lipocalin (TL) and von Ebner’s gland protein (VEG), as it is also a major secretion of these lingual salivary glands. In addition to lacrimal glands and lingual glands, Lipocalin-1 is secreted by nasal mucosal glands, secretory glands of the tracheobronchial tract, sweat glands, mammary glands, adrenal gland, prostate, thymus, testis and corticotrophs of the pituitary gland. Specifically, Lipocalin-1 functions to stabilize the lipid film of human tear fluid by removing harmful lipids from the human corneal surface and delivering them to the aqueous phase of tears. Lipocalin-1 may also function as a transporter of hydrophobic molecules such as bitter substances on the tongue. Function: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. Subunit: Homodimer. Binds to LMBR1L which may mediate its endocytosis. Subcellular Location: Secreted. Tissue Specificity: Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate. Similarity: Belongs to the calycin superfamily. Lipocalin family. SWISS: P31025 Gene ID: 3933 Database links: Entrez Gene: 3933 Human Omim: 151675 Human SwissProt: P31025 Human Unigene: 530311 Human |
