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Membralin Rabbit pAb (bs-11322R)  
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50ul/1180.00元
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產品編號 bs-11322R
英文名稱 Membralin Rabbit pAb
中文名稱 高度保守基因相關蛋白Membralin抗體
別    名 ASBABP1; C19orf6; MGC4022; R32184_3; aspecific BCL2 ARE-binding protein 1; C19orf6; chromosome 19 open reading frame 6; MBRL; MBRL_HUMAN.  
研究領域 腫瘤  細胞生物  神經生物學  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Zebrafish,Dog)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 68 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Membralin: 161-260/620 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.

Function:
Membralin has been reported to be a protein expressed in the central nervous system and has also been identified as a novel tumor associated marker in ovarian serous carcinomas.

Subcellular Location:
Membrane; Multi-pass membrane protein. Cytoplasm.Note=Cytoplasmic according to PubMed:16084606.

SWISS:
Q4ZIN3

Gene ID:
91304

Database links:

Entrez Gene: 91304 Human

Omim: 611011 Human

SwissProt: Q4ZIN3 Human

Unigene: 515003 Human



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