| 產品編號 | bs-13707R |
| 英文名稱 | PRELP Rabbit pAb |
| 中文名稱 | PRELP蛋白抗體 |
| 別 名 | 55 kDa leucine rich repeat protein of articular cartilage; MST161; MSTP161; Prelp; PRELP_HUMAN; Prolargin; Prolargin proteoglycan; Proline arginine rich end leucine rich repeat protein; Proline-arginine-rich end leucine-rich repeat protein; Proline/argini |
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Specific References (1) | bs-13707R has been referenced in 1 publications.
[IF=6.208] Andressa V. B. Nogueira. et al. Obesity Modifies the Proteomic Profile of the Periodontal Ligament. INT J MOL SCI. 2023 Jan;24(2):1003 IHC ; Rat.
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| 研究領域 | 細胞生物 信號轉導 細胞外基質 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Cow,Horse) |
| 產品應用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 42 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRELP: 151-250/382 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
PRELP (proline/arginine-rich end leucine-rich repeat protein), also known as Prolargin, MST161, SLRR2A or MSTP161, is a 382 amino acid secreted protein that localizes to the extracellular matrix. Belonging to the Class II subfamily of the small leucine-rich proteoglycan (SLRP) family, PRELP contains twelve LRR (leucine-rich) repeats, which are motifs consisting of 20-29 residues that are present in numerous proteins with diverse functions and provide versatile structural framework for the formation of protein-protein interactions. Highly expressed in cartilage, basement membranes and developing bone, PRELP is considered a glycosaminoglycan (GAG)- and collagen-binding anchor protein that associates with the basement membrane heparan sulfate proteoglycan perlecan. PRELP acts as a linker between the extracellular matrix and the cell surface of proteoglycans and may be partially responsible for Hutchinson-Gilford progeria (HGP), an extremely rare genetic disorder that causes premature, rapid aging shortly after birth. Function: May anchor basement membranes to the underlying connective tissue. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Connective tissue. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. Contains 12 LRR (leucine-rich) repeats. SWISS: P51888 Gene ID: 5549 Database links: Entrez Gene: 5549 Human Omim: 601914 Human SwissProt: P51888 Human Unigene: 632481 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
