| 產(chǎn)品編號(hào) | bs-8621R |
| 英文名稱 | PDE3B Rabbit pAb |
| 中文名稱 | 環(huán)核苷酸磷酸二酯酶PDE3B抗體 |
| 別 名 | 5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodie |
 |
Specific References (1) | bs-8621R has been referenced in 1 publications.
[IF=7.419] Mingyan Shao. et al. Ginsenoside Rb3 upregulates sarcoplasmic reticulum Ca2+-ATPase expression and improves the contractility of cardiomyocytes by inhibiting the NF-κB pathway. BIOMED PHARMACOTHER. 2022 Oct;154:113661 WB ; Mouse, Rat.
|
| 研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 124 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDE3B: 451-550/1112 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation. Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Subcellular Location: Membrane. Tissue Specificity: Abundant in adipose tissues. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. SWISS: Q13370 Gene ID: 5140 Database links: Entrez Gene: 5140 Human Entrez Gene: 18576 Mouse Omim: 602047 Human SwissProt: Q13370 Human SwissProt: Q61409 Mouse SwissProt: Q8CIX5 Mouse Unigene: 445711 Human Unigene: 430730 Mouse Unigene: 10322 Rat |
| 產(chǎn)品圖片 |
Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti- PDE3B (bs-8621R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 124 kD
Observed band size: 124 kD
Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti- PDE3B (bs-8621R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 124 kD
Observed band size: 124 kD
|
