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EIF2G Rabbit pAb (bs-14540R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-14540R
英文名稱(chēng) EIF2G Rabbit pAb
中文名稱(chēng) EIF2G蛋白抗體
別    名 eIF-2-gamma X; eIF-2gA; eIF-2gX; EIF2; EIF2G; EIF2gamma; Eif2s3; Eukaryotic translation initiation factor 2 gamma; Eukaryotic translation initiation factor 2 gamma subunit; Eukaryotic translation initiation factor 2 subunit 3; Eukaryotic translation initi  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)運(yùn)蛋白  表觀(guān)遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 51 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EIF2G: 21-120/472 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]

Function:
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B

Subunit:
Heterotrimer composed of an alpha, a beta and a gamma chain.

Similarity:
Belongs to the GTP-binding elongation factor family. EIF2G subfamily.

SWISS:
P41091

Gene ID:
1968

Database links:

Entrez Gene: 1968 Human

Entrez Gene: 26905 Mouse

Entrez Gene: 26908 Mouse

Entrez Gene: 100312984 Rat

Entrez Gene: 299027 Rat

Omim: 300161 Human

SwissProt: P41091 Human

SwissProt: Q9Z0N1 Mouse

SwissProt: P81795 Rat

Unigene: 539684 Human

Unigene: 218851 Mouse

Unigene: 250909 Mouse

Unigene: 220237 Rat

Unigene: 87025 Rat



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