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HIVEP1 Rabbit pAb (bs-17459R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-17459R
英文名稱 HIVEP1 Rabbit pAb
中文名稱 艾滋病病毒EP1抗體
別    名 Cirhin interaction protein; CIRIP; CRYBP1; GAAP; Gate keeper of apoptosis-activating protein; HIV EP1; HIV-EP1; HIVEP 1; Hivep1; Human immunodeficiency virus type I enhancer binding protein 1; Human immunodeficiency virus type I enhancer-binding protein 1  
研究領域 細胞生物  轉錄調節(jié)因子  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 297 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HIVEP1: 2001-2100/2718 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

Subcellular Location:
Cytoplasm. Nucleus and Nucleus.

Similarity:
Contains 5 C2H2-type zinc fingers.

SWISS:
P15822

Gene ID:
3096

Database links:

Entrez Gene: 3096 Human

Omim: 194540 Human

SwissProt: P15822 Human

Unigene: 567284 Human



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