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EP4, FITC conjugated (bs-24918R-FITC)  
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100ul/2980.00元
大包裝/詢價
產品編號 bs-24918R-FITC
英文名稱 EP4, FITC conjugated
中文名稱 前列腺素E受體蛋白4抗體
別    名 Prostaglandin E Receptor EP4; EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER 2; PTGER 4; PTGER2; PTGER4.  
研究領域 信號轉導  G蛋白偶聯(lián)受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse EP4: 1-100/513 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

Function:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

Subunit:
Interacts with FEM1A.

Subcellular Location:
Cell membrane.

Tissue Specificity:
High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.

Post-translational modifications:
Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P32240

Gene ID:
19219

Database links:

Entrez Gene: 5734 Human

Entrez Gene: 19219 Mouse

Entrez Gene: 84023 Rat

Entrez Gene: 443222 Sheep

Omim: 601586 Human

SwissProt: P35408 Human

SwissProt: P32240 Mouse

SwissProt: P43114 Rat

Unigene: 199248 Human

Unigene: 18509 Mouse

Unigene: 16062 Rat



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