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Rabbit Anti-HSTF2/Biotin Conjugated antibody (bs-1409R-Bio)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1409R-Bio
英文名稱 Rabbit Anti-HSTF2/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的熱休克轉(zhuǎn)錄因子2抗體
別    名 Heat shock factor protein 2; Heat shock transcription factor 2; HSF 2; HSF2; HSTF 2; HSF2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSTF2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].

Function:
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

Subunit:
DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic during normal growth and moves to the nucleus upon activation.

Similarity:
Belongs to the HSF family.

Database links:

Entrez Gene: 3298 Human

Entrez Gene: 15500 Mouse

Omim: 140581 Human

SwissProt: Q03933 Human

SwissProt: P38533 Mouse

Unigene: 158195 Human

Unigene: 261395 Mouse

Unigene: 447362 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

轉(zhuǎn)錄調(diào)節(jié)因子(Transcriptin Regulators)
熱休克轉(zhuǎn)錄因子在熱休克反應(yīng)中的主要功能,是在熱休克基因的表達(dá)過(guò)程中啟動(dòng)基因轉(zhuǎn)錄過(guò)程,促進(jìn)熱休克蛋白的表達(dá).
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